49ers vs Seahawks prediction, props, odds: Top-rated NFL expert reveals player prop bet picks for Week 13

Bitter NFC West rivals are set to square off when the San Francisco 49ers (6-5) travel to Lumen Field to take on the Seattle Seahawks (3-8) in a key Week 13 NFL game on Sunday, November 28. Kickoff is at 4:25 p.m. ET. San Francisco needs a win to keep pace in the NFC playoff race. The 49ers are favored by three points in the latest 49ers vs. Seahawks odds from Caesars Sportsbook, and the over-under is set at 45 points. In addition to the Seahawks vs. 49ers point spread and Week 13 NFL betting lines, Caesars is also offering a plethora of prop bet options for this matchup between NFC West rivals, and SportsLine expert R.J. White has just revealed his top plays.

Looking for expert advice to sharpen your betting skills? Or do you need an edge in your fantasy league? Sign up for the SportsLine Daily newsletter NOW to get sports picks and fantasy advice delivered directly to your inbox.

White, a CBS Sports fantasy and gambling editor, ended the 2020 season on an 80-59 run on all NFL picks, returning more than $1,400 during that span. He also enters Week 13 as SportsLine's No. 5 rated NFL expert, going 55-44-2 (+800) on his last 101 NFL ATS picks. It's no surprise, as White has cashed huge twice in the world's most prestigious football handicapping competition, the Las Vegas SuperContest. Anyone who has followed his picks has seen HUGE returns.

You can see all of White's expert NFL picks and analysis HERE.

Now, White has locked in on 49ers vs. Seahawks and just revealed his top three prop bet picks for this Week 13 NFL matchup.

Which NFL teams should you back this week? And which teams should you fade? Join SportsLine now to get picks for every NFL game, every week, from the red-hot simulation model that has returned almost $8,000 for $100 players.

George Kittle Over 56.5 receiving yards (-120)

"Kittle had just one target in the win over the Vikings last week, but he topped a 90% snap rate for the first time since his return from injury. We should see his usage in the passing game rise if he continues to play almost all of the snaps. That's particularly true this week with Deebo Samuel sidelined; although Samuel saw more work as a runner than a passer over the last few weeks, his touches still have to go somewhere, and I expect Kittle to be the main beneficiary. Kittle hasn't topped 50 yards since Week 9, so this is an aggressive line -- but it's aggressive for a reason."

Looking for expert advice to sharpen your betting skills? Or do you need an edge in your fantasy league? Sign up for the SportsLine Daily newsletter NOW to get sports picks and fantasy advice delivered directly to your inbox.

DK Metcalf Over 59.5 receiving yards (-115)

"Russell Wilson is slowly improving after rushing back from his finger injury, with Seattle going from 133 net passing yards in the first game out of the bye to 180 against Arizona and then 233 last week. Part of the issue is that he's failed to click with Metcalf, one of the best receivers in the league when everything is firing on all cylinders. Metcalf has just eight catches on 20 targets for 70 yards in three games combined since Wilson's return, but OC Shane Waldron has apparently come to his senses and knows the ball needs to get into Metcalf's hands more. Injuries to the team's running backs could also force more targets to the receivers. This could be a blowup spot for the talented receiver, who topped this number in five of his first seven games and came close in the other two before his recent slump."

Who wins every NFL game? And which teams will sink your bankroll? Join SportsLine now to get NFL picks every week, all from the model that simulates every game 10,000 times and is up almost $9,000.

Jimmy Garoppolo Longest completion Under 34.5 yards (-110)

"The Seahawks have certainly struggled for much of the year, but one thing they've done is limit big plays in the passing game. There have been only five completions of more than 34 yards, and while the 49ers have the longest, that was to Deebo Samuel and came from Trey Lance. Aaron Rodgers had two of the others in the Packers' recent win over Seattle, but those were the first the Seahawks allowed in over a month. With Samuel on the shelf for this game, the odds that Garoppolo hits a big play down the field are low. He probably doesn't even have to -- the Seahawks have a massive total play differential on the season, often going three-and-out and punting the ball away only to see the other offense engineer a 10-plus play drive for a score. The 49ers should be no different, moving the ball in the short and intermediate area rather than with explosive plays."

Looking for the best picks against the spread, sharp plays on the total, and props you can take straight to the pay window? Join Jonathan Coachman on the Early Edge as he speaks with SportsLine's top handicappers to preview the day's biggest games. We promise to keep it short, sweet and to put some green in your pocket. Early Edge is in your feed every single day by 11 a.m. ET. Subscribe right here on YouTube to watch daily, plus don't miss the Early Edge specials and live shows!