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    Sun, Oct 288:25 pm UTCState Farm Stadium
    Track OnCBS Sports
    San Francisco
    49ers
    SF
    Last 5 ATS
    W/L0-0
    ATS0-0
    O/U0-0-0
    FINAL SCORE
    --
    -
    --
    Arizona
    Cardinals
    ARI
    Last 5 ATS
    W/L0-0
    ATS0-0
    O/U0-0-0
    SPREAD
    MONEYLINE
    OVER/UNDER
    Last 5 ATS
    0-0
    Win /Loss
    0-0
    0-0
    Spread
    0-0
    0-0-0
    Over / Under
    0-0-0
    Key Injuries
    Key Injuries
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    NT
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    LB
    Avatar
    SAF
    Key Injuries
    Avatar
    DE
    Avatar
    OLB
    Avatar
    LS
    SPREAD
    MONEYLINE
    OVER/UNDER

    Simulation Picks

    SPREAD
    SF @ ARI
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    MONEYLINE
    SF @ ARI
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    OVER / UNDER
    SF @ ARI
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    0%
    PUBLIC
    0%
    MONEY
    0%
    PUBLIC
    0%
    MONEY
    Over0%
    PUBLIC
    Under0%
    Over
    MONEY
    Under

    Expert Picks

    Point SpreadArizona +1 -110
    WIN
    Unit1.0
    +1727
    67-45-2 in Last 114 NFL ATS Picks
    +910
    38-28 in Last 66 SF ATS Picks
    R.J.'s Analysis:

    The Cardinals' biggest issue was the offensive play-calling, as running David Johnson into the middle of the line just isn't a smart use of his talents. With Bruce Arians disciple Byron Leftwich in charge, I expect a much better showing from the offense. The defense shined in a road matchup with the 49ers a few weeks ago, and I expect more of the same here. The 49ers just aren't getting turnovers, and the Cardinals defense is too good to drive the field on repeatedly. Cardinals should be favored in this matchup.

    Pick Made: Oct 26, 8:44 pm UTC
    Point SpreadSan Francisco -1 -110
    LOSS
    Unit1.0
    +690
    27-18-2 in Last 47 NFL Picks
    Hank's Analysis:

    Arizona is awful, while the 49ers have a good young team. It's that simple.

    Pick Made: Oct 26, 4:11 am UTC
    Point SpreadSan Francisco +1 -116
    LOSS
    Unit1.0
    Emory's Analysis:

    With new offensive coordinator Byron Leftwich calling the plays now, many in the media believe that things will magically change for the Cardinals. Maybe there will be an uptick in creativity on offense, but there are still some concerns with the defensive personnel and QB Josh Rosen has been turnove- prone and now has a banged up toe. The 49ers, on the other hand, seem to find ways to make offense happen despite clear personnel shortcomings.

    Pick Made: Oct 25, 2:11 am UTC

    Team Injuries

    San Francisco 49ers
    Tuesday, Mar 05, 2024
    Avatar
    SAF
    Tayler Hawkins
    WristQuestionable
    Avatar
    DT
    Kalia Davis
    AnkleQuestionable
    Avatar
    TE
    Cameron Latu
    Knee - MeniscusQuestionable
    Avatar
    DE
    Drake Jackson
    KneeQuestionable
    Avatar
    WR
    Danny Gray
    Shoulder - AC JointQuestionable
    Thursday, Feb 22, 2024
    Avatar
    CB
    Charvarius Ward
    UndisclosedQuestionable
    Tuesday, Feb 13, 2024
    Avatar
    NT
    Javon Hargrave
    ThumbQuestionable
    Avatar
    OT
    Nick Zakelj
    BicepsQuestionable
    Avatar
    SAF
    Talanoa Hufanga
    Knee - ACLQuestionable
    Monday, Feb 12, 2024
    Avatar
    LB
    Dre Greenlaw
    AchillesQuestionable
    Arizona Cardinals
    Friday, Mar 08, 2024
    Avatar
    DE
    L.J. Collier
    BicepsQuestionable
    Tuesday, Mar 05, 2024
    Avatar
    LS
    Matt Hembrough
    BackQuestionable
    Avatar
    OG
    Jon Gaines II
    KneeQuestionable
    Avatar
    DT
    Dante Stills
    KneeQuestionable
    Avatar
    CB
    Garrett Williams
    AnkleQuestionable
    Monday, Feb 12, 2024
    Avatar
    OLB
    Kyzir White
    ElbowQuestionable