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    Sun, Sep 235:00 pm UTCGEHA Field at Arrowhead Stadium
    Track OnCBS Sports
    San Francisco
    49ers
    SF
    Last 5 ATS
    W/L0-0
    ATS0-0
    O/U0-0-0
    FINAL SCORE
    --
    -
    --
    Kansas City
    Chiefs
    KC
    Last 5 ATS
    W/L0-0
    ATS0-0
    O/U0-0-0
    SPREAD
    MONEYLINE
    OVER/UNDER
    Last 5 ATS
    0-0
    Win /Loss
    0-0
    0-0
    Spread
    0-0
    0-0-0
    Over / Under
    0-0-0
    Key Injuries
    Key Injuries
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    NT
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    LB
    Avatar
    SAF
    Key Injuries
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    OG
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    DE
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    WR
    SPREAD
    MONEYLINE
    OVER/UNDER

    Simulation Picks

    SPREAD
    SF @ KC
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    MONEYLINE
    SF @ KC
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    OVER / UNDER
    SF @ KC
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    0%
    PUBLIC
    0%
    MONEY
    0%
    PUBLIC
    0%
    MONEY
    Over0%
    PUBLIC
    Under0%
    Over
    MONEY
    Under

    Expert Picks

    Point SpreadKansas City -6.5 -114
    WIN
    Unit1.0
    +484
    8-3 in Last 11 NFL ATS Picks
    +530
    11-4 in Last 15 KC ATS Picks
    Kenny's Analysis:

    The Patrick Mahomes era has started with a bang. Mahomes has so many talented offensive players around him it will take at least 3-4 more weeks before teams start to figure out how to corral this offense. I'm sure being as physical as possible with their smallish playmakers will slow them down in weeks to come but San Francisco is not the team to be physical. Mahomes throws four more touchdowns and yes the defensive numbers are poor for Kansas City but it's been in prevent defense for the better part of two quarters versus their first two foes.

    Pick Made: Sep 22, 6:16 pm UTC
    Over / UnderUNDER 55 -110
    LOSS
    Unit1.0
    +732
    15-7-1 in Last 23 NFL Picks
    +390
    5-1 in Last 6 NFL O/U Picks
    Zack's Analysis:

    An area bettors go wrong all the time is chasing a downfall instead of riding it. Kansas City’s defense is showing no signs of improving and their offense is showing no signs of slowing down. They’ll face a San Francisco team that is still not near their ceiling offensively. This has another fast-paced, points-galore game written all over it. Yet the oddsmakers have this line precise and will win the Under based on special teams miscues and an ill-advised turnover. Grab the under.

    Pick Made: Sep 22, 1:30 pm UTC
    Point SpreadSan Francisco +6.5 -107
    LOSS
    Unit1.0
    +459
    10-5-2 in Last 17 NFL ATS Picks
    +550
    6-0 in Last 6 SF ATS Picks
    Mike's Analysis:

    The Chiefs might have the best offense in the league to start the season. The Chiefs might have the worst defense in the league to start the season. Kansas City has scored 80 points and still has a NEGATIVE 9.6 net yards per drive this season. This defense is miserable. Opposing defenses now have two weeks of game film on Mahomes. Kyle Shanahan and Jimmy G will have enough to get the cover and possibly win outright on the road in Kansas City.

    Pick Made: Sep 22, 7:56 am UTC
    Point SpreadSan Francisco +6.5 -107
    LOSS
    Unit1.0
    +1727
    67-45-2 in Last 114 NFL ATS Picks
    +910
    38-28 in Last 66 SF ATS Picks
    R.J.'s Analysis:

    I'm a big fan of the Chiefs' offense, but their defense has given up a ton of points, particularly in the second half. That's good news for the 49ers, who have a quarterback in Jimmy Garoppolo who can get some garbage-time touchdowns if needed and help us cover this line. The 49ers defense is getting whole, with linebackers Reuben Foster and Malcolm Smith back for this game. I like Kyle Shanahan to come up with more than enough to hang a big number here and get us a cover.

    Pick Made: Sep 21, 9:36 pm UTC
    Over / UnderOVER 55.5 -110
    WIN
    Unit1.0
    Micah's Analysis:

    This massive total sticks out like a sore thumb on the betting board, but it might not be high enough. New QB Patrick Mahomes is in the middle of an epic groove and I don't see the 49ers stopping him any better than the Chiefs or Steelers did. The main reason this game gets Over is because of the Chiefs defense allowing 32.5 ppg and 508 ypg. Jimmy Garoppolo will have some fun in the Chiefs' home opener. Over is the play.

    Pick Made: Sep 20, 9:47 pm UTC
    Over / UnderUNDER 56 -104
    LOSS
    Unit1.0
    +102
    10-8 in Last 18 NFL Picks
    +735
    15-7 in Last 22 SF O/U Picks
    Mike's Analysis:

    This is the week in which Chiefs QB Patrick Mahomes floats back to earth -- or at least below the cloud line. Ten TD passes and no interceptions, with road wins over Super Bowl contenders Los Angeles (Chargers version) and Pittsburgh, is otherworldly. Still, totals this high should be reserved for games involving dreadful defenses, and these two are respectable. Nine sacks suffered by 49ers QB Jimmy Garoppolo is stunting the Niners’ offense. The rise from 52.5 points enhances value on the Under in Sunday's game.

    Pick Made: Sep 18, 11:46 pm UTC

    Team Injuries

    San Francisco 49ers
    Tuesday, Mar 05, 2024
    Avatar
    SAF
    Tayler Hawkins
    WristQuestionable
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    DT
    Kalia Davis
    AnkleQuestionable
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    TE
    Cameron Latu
    Knee - MeniscusQuestionable
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    DE
    Drake Jackson
    KneeQuestionable
    Avatar
    WR
    Danny Gray
    Shoulder - AC JointQuestionable
    Thursday, Feb 22, 2024
    Avatar
    CB
    Charvarius Ward
    UndisclosedQuestionable
    Tuesday, Feb 13, 2024
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    NT
    Javon Hargrave
    ThumbQuestionable
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    OT
    Nick Zakelj
    BicepsQuestionable
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    SAF
    Talanoa Hufanga
    Knee - ACLQuestionable
    Monday, Feb 12, 2024
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    LB
    Dre Greenlaw
    AchillesQuestionable
    Kansas City Chiefs
    Tuesday, Mar 05, 2024
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    WR
    Marquise Brown
    HeelQuestionable
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    FS
    Bryan Cook
    AnkleQuestionable
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    LB
    Cam Jones
    ChestQuestionable
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    WR
    Nikko Remigio
    WristQuestionable
    Monday, Feb 12, 2024
    Avatar
    OG
    Joe Thuney
    PectoralQuestionable
    Avatar
    DE
    Charles Omenihu
    Knee - ACLQuestionable