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    Sun, Sep 095:00 pm UTCU.S. Bank Stadium
    Track OnCBS Sports
    San Francisco
    49ers
    SF
    Last 5 ATS
    W/L0-0
    ATS0-0
    O/U0-0-0
    FINAL SCORE
    --
    -
    --
    Minnesota
    Vikings
    MIN
    Last 5 ATS
    W/L0-0
    ATS0-0
    O/U0-0-0
    SPREAD
    MONEYLINE
    OVER/UNDER
    Last 5 ATS
    0-0
    Win /Loss
    0-0
    0-0
    Spread
    0-0
    0-0-0
    Over / Under
    0-0-0
    Key Injuries
    Key Injuries
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    NT
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    LB
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    SAF
    Key Injuries
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    OT
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    OLB
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    TE
    SPREAD
    MONEYLINE
    OVER/UNDER

    Simulation Picks

    SPREAD
    SF @ MIN
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    Maximize Your Odds of Winning with SportsLine Model and Our Top-Rated Picks!

    MONEYLINE
    SF @ MIN
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    Maximize Your Odds of Winning with SportsLine Model and Our Top-Rated Picks!

    OVER / UNDER
    SF @ MIN
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    0%
    PUBLIC
    0%
    MONEY
    0%
    PUBLIC
    0%
    MONEY
    Over0%
    PUBLIC
    Under0%
    Over
    MONEY
    Under

    Understanding

    Public and Money

    Read More

    Think of 'Public' as the percentage of people betting on each side and 'Money' as how much money is being bet. When there's a big difference between the 'Public' and 'Money' data, it usually means that the more serious bettors (referred to as 'Sharp Money') are favoring a particular side.

    Expert Picks

    Point SpreadSan Francisco +6 -105
    LOSS
    Unit1.0
    +390
    9-5 in Last 14 SF ATS Picks
    Josh's Analysis:

    Although I'm not necessarily buying the hype on the 49ers as a playoff contender as their season-win total odds (9) suggest, they should be improved and in the game to the wire Sunday. The Vikings made a lateral -- at best -- move at quarterback in Kirk Cousins, though he he has plenty of weapons to work with. This is just a bit too steep of a line, and the Vikings might be the biggest public side in Week 1.

    Pick Made: Sep 09, 4:05 pm UTC
    Point SpreadMinnesota -6 -105
    WIN
    Unit1.0
    +476
    8-3-1 in Last 12 SF ATS Picks
    Adam's Analysis:

    There is no part of me that believes in Jimmy Garoppolo -- at least to the extent that 49ers fans appear to. In six games with San Francisco last year, he threw seven touchdowns and five picks. Candidly, I'm surprised this is not a touchdown spread with the Vikings at home and Mike Zimmer basically getting all offseason to game plan for Week 1. The 24-10 ATS mark at home is not lost on me, and neither is a strong Vikings defense that should help them earn a clean win to open the season. Let's also not forget who the 49ers just lost on offense.

    Pick Made: Sep 09, 4:05 pm UTC
    Over / UnderUnder 46 -110
    WIN
    Unit1.0
    +102
    10-8 in Last 18 NFL Picks
    +735
    15-7 in Last 22 SF O/U Picks
    Mike's Analysis:

    Now we'll see how good the newly anointed one, 49ers quarterback Jimmy Garoppolo, really is. The test in Minnesota was already daunting, what with the Vikes having yielded a mere 12.5 points per game at home last season. A season-ending injury to the 49ers' second-least-dispensable offensive player, running back Jerrick McKinnon, puts Jimmy G behind the eight ball. The Vikings do not need a smashing debut from its new quarterback Kirk Cousins. Effective game management that generates 24 points or so will suffice in a matchup that should wind up south of 40 points.

    Pick Made: Sep 08, 5:47 pm UTC
    Point SpreadMinnesota -6.5 -110
    WIN
    Unit1.0
    Micah's Analysis:

    The secret to Mike Zimmer's success (44-21 ATS) entering his fifth season has been a conservative offense. It's part of the reason I don't like the move to get Kirk Cousins. But the home-field edge is huge in Minnesota and its defense is the best. The Vikings are 15-4 ATS in the last three seasons as home favorites. The 49ers won their final five games last season, but in at least four of them, it was circumstantial due to a key player being out or a team resting starters. I'm on the Vikings to take care of business at home.

    Pick Made: Sep 08, 5:26 pm UTC
    Point SpreadMinnesota -6.5 -110
    WIN
    Unit1.0
    +1727
    67-45-2 in Last 114 NFL ATS Picks
    +2450
    54-27-5 in Last 86 MIN ATS Picks
    R.J.'s Analysis:

    Not a believer in the 49ers defense, especially with Reuben Foster out and several key defensive linemen dealing with injuries in the preseason. The Vikings should be able to move the ball with ease against this unit, while I have a hard time imagining the 49ers doing the same against the Vikings' elite defense, especially in Minnesota. I think we'll look back at this line in a few weeks and wonder why it was where it was and not in double-digits.

    Pick Made: Sep 05, 10:06 pm UTC
    Point SpreadMinnesota -6 -110
    WIN
    Unit1.0
    +843
    61-47-3 in Last 111 NFL Picks
    +690
    56-44-3 in Last 103 NFL ATS Picks
    +1910
    39-18-2 in Last 59 MIN ATS Picks
    Larry's Analysis:

    This line should be 7, and I won't be surprised if it gets there by kickoff. While I normally hate laying big points in Week 1, it's warranted in this case. The 49ers' strong 2017 finish and offseason hype certainly played a role in keeping the line under 7. Now they face the league's No. 1 defense in Minnesota, where the Vikings are 24-10 ATS under Mike Zimmer. Look for Kirk Cousins to go right after 30-year-old Richard Sherman and for the new-look Minny offense to make a slew of big plays.

    Pick Made: Aug 30, 8:45 pm UTC

    Team Injuries

    San Francisco 49ers
    Monday, Apr 15, 2024
    Avatar
    SAF
    Tayler Hawkins
    WristQuestionable
    Monday, Apr 01, 2024
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    DT
    Kalia Davis
    AnkleQuestionable
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    TE
    Cameron Latu
    Knee - MeniscusQuestionable
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    DE
    Drake Jackson
    KneeQuestionable
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    WR
    Danny Gray
    Shoulder - AC JointQuestionable
    Monday, Mar 25, 2024
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    TE
    George Kittle
    GroinQuestionable
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    CB
    Charvarius Ward
    GroinQuestionable
    Tuesday, Feb 13, 2024
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    NT
    Javon Hargrave
    ThumbQuestionable
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    OT
    Nick Zakelj
    BicepsQuestionable
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    SAF
    Talanoa Hufanga
    Knee - ACLQuestionable
    Monday, Feb 12, 2024
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    LB
    Dre Greenlaw
    AchillesQuestionable
    Minnesota Vikings
    Monday, Apr 01, 2024
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    OT
    Brian O'Neill
    FootQuestionable
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    OG
    Ed Ingram
    ShoulderQuestionable
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    DB
    Theo Jackson
    ToeQuestionable
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    CB
    NaJee Thompson
    KneeQuestionable
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    DB
    Mekhi Blackmon
    ShoulderQuestionable
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    WR
    Malik Knowles
    UndisclosedQuestionable
    Avatar
    WR
    Jalen Nailor
    ConcussionQuestionable
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    DT
    Jaquelin Roy
    AnkleQuestionable
    Thursday, Mar 14, 2024
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    OLB
    Andrew Van Ginkel
    FootQuestionable
    Tuesday, Feb 13, 2024
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    TE
    T.J. Hockenson
    Knee - ACL + MCLQuestionable
    Tuesday, Jan 30, 2024
    Avatar
    CB
    Byron Murphy
    Knee - MCLQuestionable