Simulation Picks
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Expert Picks
Look for the Bills to control the time of possession and dictate the pace of the game with their ground attack.
The Bills were a push for me after I went against them as nine-point favorites at home against the Jets, the worst team in the league. The Bills proved they aren't the worst team in the league, but I'm not sure they'll be competitive against good teams, especially on the road. That's exactly what the Panthers are, and the Carolina defense could shut down Buffalo just as badly as it did San Francisco in Week 1. Panthers roll.