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Virginia vs. Louisville odds, line, spread: Proven model reveals college basketball picks, predictions for Jan. 24, 2022

The SportsLine projection model has a pick for the clash between Louisville and Virginia
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An ACC battle is on tap between the Virginia Cavaliers and the Louisville Cardinals at 7 p.m. ET on Monday at John Paul Jones Arena. Virginia is 11-8 overall and 6-4 at home, while Louisville is 11-8 overall and 2-4 on the road. Both teams are tied for seventh place in the ACC. 

The Cavaliers are favored by 5 points in the latest Virginia vs. Louisville odds from Caesars Sportsbook, while the over-under is set at 125. Before you make any Louisville vs. Virginia picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $2,400 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Virginia vs. Louisville 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Louisville vs. Virginia? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.

So who wins Louisville vs. Virginia? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.

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SportsLine Staff