The Villanova Wildcats can move into first place in the Big East standings when they host the struggling DePaul Blue Demons on Tuesday at Finneran Pavilion in Villanova, Pa. Ranked No. 4 in the preseason, the Wildcats (14-5, 7-2 Big East) enter the game tied with Providence (16-2, 6-1) in the conference standings. Meanwhile the Blue Demons (10-8, 1-7) sit in 10th place in the 11-team Big East. 

Ti-off is set for 7 p.m. ET. The Wildcats are favored by 17.5 points in the latest Villanova vs. DePaul odds from Caesars Sportsbook, while the Over/Under for total points scored is down to 133.5. (See up-to-date odds for every game this week on our college basketball odds page.)

Before making any DePaul vs. Villanova picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Div. I college basketball game 10,000 times. It enters Week 12 of the season with a 49-36 record on all top-rated college basketball picks, returning almost $700. Over the past five-plus years, the proprietary computer model has generated an impressive profit of $2,800 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows that Villanova has one of the oldest starting lineups in the country. The Wildcats start two fifth-year seniors, another senior, a junior and a redshirt sophomore. Their top bench player, Caleb Daniels, also is a fifth-year senior.

The model also knows that DePaul has one of the Big East's most prolific scorers in Javon Freeman-Liberty. A 6-foot-4 senior from Chicago, Freeman-Liberty leads the conference and ranks ninth in the country in points per game (21.1). In the first game against Villanova this season, he torched the Wildcats for 22 points in the first half.

Now, the model has set its sights on Villanova vs. DePaul. We can tell you it is leaning Over the total, predicting a combined 142 points, and it also says one side of the spread covers in well over 50 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Villanova vs. Depaul? And which side of the spread covers in well over 50 percent of simulations? ... Join SportsLine right now to find out which side of the DePaul vs. Villanova spread you should be all over Tuesday, all from the model on a roll on college basketball picks!