The UNLV Rebels will take on the Iowa State Cyclones on Saturday, September, 18 at 10:30 p.m. ET next Saturday at Allegiant Stadium in Las Vegas. The Cyclones (1-1) ended last year first in the Big 12, while UNLV (0-2) ended up 12th in the Mountain West Conference. 

Iowa State is favored by 30 points in the latest UNLV vs. Iowa State odds from Caesars Sportsbook, and the over-under is set at 52. Before you make any Iowa State vs. UNLV picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of over $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 3 of the 2021 season on a 67-50 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, it has simulated UNLV vs. Iowa State 10,000 times and the results are in. We can tell you that the model is leaning over on the point total, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins UNLV vs. Iowa State? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!