The year's final major, the U.S. Open, begins Monday, Aug. 26 from Flushing Meadow, N.Y. Serena Williams enters as the 5-1 favorite, followed by Ash Barty (15-2), Simona Halep (15-2), Naomi Osaka (12-1), Madison Keys (16-1), Karolina Pliskova (16-1), Bianca Andreescu (18-1) and Petra Kvitova (18-1).

Before you bet, you NEED to see who Gavin Mair picked. Not only did the famed international tennis expert call Naomi Osaka winning last year's U.S. Open at 32-1, but $100 bettors who have tailed his U.S. Open picks that past two years are up a tidy $4,450!

Now, Mair has broken down the latest U.S. Open 2019 odds and released his coveted best bets to win it all.

One huge shocker: Mair wants no part of the favored Williams, who has 23 Grand Slam singles titles on her resume. "Serena Williams is, as she tends to be, guarded about her well-being, but recent evidence suggests her body is more susceptible to breaking down the longer a tournament goes on," Mair told SportsLine. "This was the case in Toronto, where she made it to the final only to retire at the start of her match with Bianca Andreescu."

Instead, Mair is backing three players who are 16-1 to win or higher, including a 22-year-old, ASTRONOMICAL long shot he described this way: "An incredible talent who will win Grand Slam titles." You ABSOLUTELY need to see who Mair's backing before locking in your U.S. Open picks.

Who wins the 2019 U.S. Open? And which MASSIVE long shots stun the tennis world? ... Join SportsLine right now to see Gavin Mair's best bets for the U.S. Open women's crown, all from the acclaimed expert who called Naomi Osaka winning last year's U.S. Open at 32-1! -- Use promo code TENNIS to get your first month of SportsLine for a buck!