Week 2 of the 2022 NFL season kicks off with Thursday Night Football between the Los Angeles Chargers and Kansas City Chiefs. The game will be played at Arrowhead Stadium in Kansas City and kickoff is scheduled for 8:15 p.m. ET in a meeting of two of the league's best quarterbacks -- Patrick Mahomes and Justin Herbert. This game also features plenty of impressive skill players such as Travis Kelce, Austin Ekeler and Mike Williams, though Keenan Allen (hamstring) has been ruled out for the Chargers. 

There are plenty of ways to get in on the action for this primetime showdown. One of the bet types growing in popularity is the same-game parlay, which combine picks like spread, total, money line and props for the chance at a huge payout.

Before locking in any same-game parlays for Chiefs vs. Chargers, you NEED to see what Mike McClure has to say.

McClure is a legendary professional DFS player with over $2 million in career winnings. His methodology has led to enormous cashes on FanDuel and DraftKings. He took down two high-stakes tournaments on FanDuel in 2020 and recorded a pair of top-10 finishes in tournaments with over 130,000 entrants on DraftKings. His lineups also finished inside the top 1 percent in more than a dozen other tournaments.

He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends and injuries into account. This allows him to find the best same-game parlay picks that he shares with SportsLine users. 

Now, McClure has turned his attention to Chiefs vs. Chargers on Thursday Night Football and locked in his top single-game parlay picks. 

We can tell you part of McClure's same-game parlay is to go Over on the alternate totals of 49.5 receiving yards for Williams and 64.5 receiving yards for Travis Kelce. Williams should be in line for a big game with Allen sitting this one out. Kelce was a nightmare matchup for the Cardinals last week as he piled up an 8-121-1 receiving line, and McClure feels very comfortable with these players sailing over these numbers. 

McClure is also targeting FIVE other picks in his same-game parlay and the final payout comes out to +500! You ABSOLUTELY need to see who it is before locking in any lineups.

What is top same-game parlay combination for Chargers vs. Chiefs? And which overlooked player props do you need to be all over? ... Join SportsLine now to see DFS pro Mike McClure's top same-game parlay picks, all for a shot at a massive +500 return!