The rival Boston Red Sox and New York Yankees play the middle game of their three-game series when they square off on Saturday night at Fenway Park in Boston. First pitch is at 7:15 p.m. William Hill Sportsbook lists Boston as the -125 favorite (risk $125 to win $100) in the latest Red Sox vs. Yankees odds while New York is a +115 underdog. The Over-Under for total runs scored is 10. (See the latest lines for every game on our MLB odds page.)

Before making any Yankees vs. Red Sox picks, you NEED to see the latest MLB predictions from the SportsLine Projection Model.

This model, which simulates every pitch of every game 10,000 times, had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line picks. It's off to a sizzling start in 2021, going 100-74 on top-rated MLB money-line picks through 12 weeks, returning more than $1,200. Anyone following it has seen huge returns.

Now, it has set its sights on Red Sox vs. Yankees. We can tell you it's leaning Under the total, and it also says one side of the money line has all the value! You ABSOLUTELY need to see it before locking in any MLB picks of your own.

So who wins Red Sox vs. Yankees? And which side of the money line has all the value? ... Join SportsLine right now to find out which side of the Yankees vs. Red Sox money line you should be all over on Saturday, all from the model that is up more than $1,200 on MLB picks this season!