The 49ers will take on the Bengals at 1 p.m. ET on Sunday at Paul Brown Stadium. Cincinnati is favored by 1.5-points in the latest 49ers vs. Bengals odds, while the Over-Under is set at 45.5. Before you make any 49ers vs. Bengals picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The model, which simulates every NFL game 10,000 times, is up over $7,000 for $100 players on its top-rated NFL picks since its inception four years ago. It has nailed its recent top-rated NFL picks, entering Week 2 of the 2019 NFL season on a sizzling 17-6 run that dates back to last season. It's also on a strong 79-49 roll on top-rated picks. The model ranked in the top 10 on NFLPickWatch for the third straight year on straight-up NFL picks and beat over 96 percent of CBS Sports office pool players. Anyone who has followed it is way up.

Now, it has simulated 49ers vs. Bengals 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread is hitting in over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Bengals vs. 49ers? And which side of the spread is hitting in over 50 percent of simulations? ... Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks.