The Pittsburgh Pirates and the St. Louis Cardinals round out their four-game opening series at 2:15 p.m. ET on Monday. St. Louis is listed as a -180 favorite (risk $180 to $100) at Caesars Sportsbook, while the Over-Under is set at eight runs (see up-to-date odds for every game this week on our MLB odds page). 

Before making any Pirates vs. Cardinals picks, you NEED to check out the MLB predictions from the SportsLine Projection Model.

This model, which simulates every game 10,000 times, enters Week 2 of the 2022 season on a 216-181 roll on top-rated MLB money-line picks that dates back to last season, returning over $900 for $100 players. Anyone following it has seen HUGE returns!

The model knows St. Louis has a solid offensive unit. They have scored four-plus runs in each game thus far. St. Louis is currently sixth in batting average (.263) and tied for fourth in on-base percentage (.351). The Cardinals are also tied for fifth with five home runs. Third baseman Nolan Arenado has a .500 batting average and drove in seven runs through the first three games. 

The model also knows Pittsburgh's offense has some talented hitters. The Pirates rank fourth in the league in batting average (.283). Third baseman Ke'Bryan Hayes has gotten two hits in back-to-back games and sits with a batting average of .400. Hayes also plays good defense and has a strong arm to deliver the baseball across the diamond with ease. 

Now, it has set its sights on Pirates vs. Cardinals. We can tell you the model is leaning over the total, and it also says one side of the money line has all the value. You ABSOLUTELY need to see it before locking in any MLB picks.

So who wins Cardinals vs. Pirates? And which side of the money line has all the value? Join SportsLine here to find out, all from the model that has crushed its top-rated MLB money-line picks!