The Penn State Nittany Lions will take on the Ball State Cardinals at 3:30 p.m. ET on Saturday at Beaver Stadium. The Nittany Lions are favored by 22.5 points in the latest Penn State vs. Ball State odds from Caesars Sportsbook, and the over-under is set at 57.5. Before you make any Ball State vs. Penn State picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of over $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 2 of the 2021 season on a 63-45 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, it has simulated Penn State vs. Ball State 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Penn State vs. Ball State? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!