The NFL's two longest-tenured coaches will meet on Sunday when Bill Belichick and the New England Patriots host Sean Payton and the New Orleans Saints. New England (1-1) is coming off a 25-6 win at the Jets, while New Orleans (1-1) enters Week 3 off a 26-7 loss at Carolina. Kickoff is 1 p.m. ET. New England is a 2.5-point favorite in the latest Patriots vs. Saints odds from Caesars Sportsbook, while the Over-Under for total points scored is 43.5. (See the latest NFL lines for every game this week on our NFL odds page.)

Before you make any Saints vs. Patriots picks, you NEED to check out the latest NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up almost $7,800 for $100 players on top-rated NFL picks since its inception six-plus years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters Week 3 of the 2021 season on an incredible 122-81 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP.

The model knows New England defense has been solid to start the season. The Patriots are allowing just 297.5 total yards per game, which ranks fifth in the NFL. In Sunday's victory against the Jets, New England had four interceptions, four sacks and allowed just six points.

The model also knows that New Orleans has played well recently as the underdog. Since the start of the 2018 season, the Saints are 9-2 straight-up when they are not favored, including a 35-point win against Green Bay in Week 1 of this season. The 9-2 record is the best in the NFL in that span.

Now, the model has set its sights on Patriots vs. Saints. We can tell you it's leaning Under the total, and it also says one side of the spread has ALL the value! You ABSOLUTELY need to see it before locking in any NFL picks of your own.

So who wins Patriots vs. Saints on Sunday? And which side of the spread has ALL the value? ... Join SportsLine right now to find out which side of the Saints vs. Patriots spread you should be all over, all from the advanced model that has returned almost $7,800 on top-rated NFL picks!