The No. 3 Ohio State Buckeyes will try to stay on track to make the College Football Playoff when they take on the Michigan State Spartans on Saturday at Spartan Stadium in East Lansing, Mich. Kickoff is set for noon ET. William Hill Sportsbook pegs the Buckeyes as 23.5-point favorites in the latest odds, while the Over-Under for total points scored is 59.5. (Find the latest college football lines for every game this week on our college football odds page.) 

Before making any Michigan State vs. Ohio State picks, you need to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past four-plus years, the proprietary computer model has generated a stunning profit of over $3,500 for $100 players on its top-rated college football picks against the spread. It is also a sizzling 49-25 on all top-rated picks through 13 weeks of the 2020 college football season, returning almost $1,300 in profit already. Anyone who has followed it has seen HUGE returns.

Now, it has set its sights on Michigan State vs. Ohio State. We can tell you it's leaning Under the total, and it's also generated an against-the-spread pick that cashes in over 50 percent of simulations! You ABSOLUTELY need to see it before locking in any college football picks of your own.

So who wins Ohio State vs. Michigan State? And which side of the spread can you bank on in over 50 percent of simulations? ... Join SportsLine right now to find out which side of the Michigan State vs. Ohio State spread to back, all from the advanced model that is a sizzling 49-25 on top-rated picks through 13 weeks of the 2020 college football season!