The Ohio State Buckeyes host the Indiana Hoosiers in a pivotal Big Ten clash at noon ET on Saturday. Ohio State is favored by 20.5 points at William Hill Sportsbook, while the Over-Under is set at 66 (see up-to-date odds for every game this week on our college football odds page). Before making any Ohio State vs. Indiana picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past four-plus years, the proprietary computer model has generated a stunning profit of almost $3,900 for $100 players on its top-rated college football picks against the spread. It is a sizzling 39-21 on top-rated picks through 11 weeks of the 2020 college football season, returning over $1,000 in profit already. Anyone who has followed it has seen HUGE returns.

Now, it has set its sights on Ohio State vs. Indiana. We can tell you the model is leaning Under the total, and it also says one side of the spread hits in over 60 percent of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

Who wins Ohio State vs. Indiana? And which side of the spread hits in over 60 percent of simulations? ... Join SportsLine right now to find out which side of the Ohio State vs. Indiana spread you should be all over Saturday, all from the model on a roll on college football picks!