The No. 22 Marquette Golden Eagles will try to stay hot when they take on the Seton Hall Pirates in a Big East conference game on Wednesday at the Prudential Center in Newark, N.J. After losing four straight games in December, the Golden Eagles (14-6, 6-3 Big East) have won six straight games, including four over teams ranked in the Top 25. Meanwhile the Pirates (12-6, 3-5) have lost three of their last four games. 

Tip-off is set for 8:30 p.m. ET. The Pirates are favored by six points in the latest Marquette vs. Seton Hall odds, while the Over/Under for total points scored is 145. (See up-to-date odds for every game this week on our college basketball odds page.)

Before making any Seton Hall vs. Marquette picks, be sure to check out what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. It enters Week 12 of the season with a 49-36 record on all top-rated college basketball picks, returning almost $700. Over the past five-plus years, the proprietary computer model has generated an impressive profit of $2,800 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows that the Pirates are one of the best free throw shooting teams in the nation. They make 76.7 percent of their free throws, which ranks second in the Big East and 26th in Div. I. That bodes well against a Marquette team that commits fouls at a high rate (17.4 per game, 234th in the country.)

The model also knows that the Golden Eagles are one of the best teams in the country at sharing the ball. Marquette averages 17.7 assists per game, which ranks second in the Big East and 10th in the country. Tyler Kolek, a transfer from George Mason, leads the conference and ranks eighth in the nation in assists per game (6.5).

Now, the model has set its sights on Marquette vs. Seton Hall. We can tell you it is leaning Under the total, predicting a combined 143 points, and it also says one side of the spread covers in well over 50 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Marquette vs. Seton Hall? And which side of the spread covers in well over 50 percent of simulations? ... Join SportsLine right now to find out which side of the Seton Hall vs. Marquette spread you should be all over Wednesday, all from the model on a roll on college basketball picks!