Week 6 of the 2022 NFL schedule features several enticing matchups, highlighted by Chiefs vs. Bills and Cowboys vs. Eagles. Buffalo is a 2.5-point favorite in the latest Week 6 NFL odds at Caesars Sportsbook, while the Eagles are 6.5-point favorites over Dallas. Other games with tight Week 6 NFL spreads include Vikings vs. Dolphins (+3), Saints vs. Bengals (-2.5) and Patriots vs. Browns (-2.5). Before making any NFL picks for Week 6, be sure to see what the SportsLine Projection Model has to say.

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 6 of the 2022 NFL season on an incredible 146-106 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP.

Now, the model has evaluated the latest odds from Caesars, simulated every snap for Week 6 of the 2022 NFL season, and the results are in. 

We can tell you one of the model's strongest Week 6 NFL picks is that the Giants (+5.5) cover the spread at home against Baltimore well over 50% of the time. Another one of its Week 6 NFL predictions: The Packers (-7.5) cover against the Jets in almost 60% of simulations. The model also says the Over (45) hits in over 60% of simulations.

The model has also made the call on who wins and covers every other NFL game this week and it identified a Super Bowl contender that goes down HARD! You ABSOLUTELY need to see its NFL picks for every single game before locking in your own.

So which NFL teams should you back this week? And which Super Bowl contender goes down? ... Join SportsLine now to see who wins and covers every single game, all from the model that has returned almost $7,000 in profit on top-rated picks since its inception!