Two teams with far different situations at quarterback will meet on Monday Night Football as the Los Angeles Chargers visit the Indianapolis Colts at 8:15 p.m. ET. Justin Herbert is firmly entrenched atop LA's depth chart and is one of the best NFL DFS picks at the position, while Indy will start its third QB of the season in Nick Foles. Before setting your NFL DFS lineups for Colts vs. Chargers you NEED to see what Mike McClure has to say.

McClure is a legendary professional DFS player with over $2 million in career winnings. His methodology has led to enormous cashes on FanDuel and DraftKings. He took down two high-stakes tournaments on FanDuel in 2020 and recorded a pair of top-10 finishes in tournaments with over 130,000 entrants on DraftKings. His lineups also finished inside the top 1% in more than a dozen other tournaments.

He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine.

This year, he's already won the DraftKings Millionaire Maker twice and the FanDuel Million once! Now, McClure has turned his attention to Colts vs. Chargers and locked in his top daily Fantasy football picks.

We can tell you that Chargers QB Herbert is one of McClure's top NFL DFS picks for Monday Night Football. Part of McClure's optimal NFL DFS strategy also includes stacking Herbert with receiver Mike Williams. Williams has averaged five grabs for 91.5 yards with 1 total touchdown across his two starts and this stack is well-positioned to take advantage of a struggling Indianapolis secondary that gave up four passing touchdowns last week.

McClure is also targeting a player who could go off for MASSIVE numbers on Monday Night Football! This pick could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who it is before locking in any lineups.

What are the top NFL DFS picks for Chargers vs. Colts on Monday Night Football? And which player is a MUST-ROSTER? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NFL DFS!