The AL East-leading Boston Red Sox kick off a three-game weekend series Friday when they host the Los Angeles Angels at Fenway Park. First pitch is set for 7:10 p.m. ET. Nick Pivetta is scheduled to pitch for Boston, opposed by Griffin Canning of Los Angeles. Boston is a -120 favorite (risk $120 to win $100), while Los Angeles is offered at +110 in the latest William Hill Sportsbook odds for Angels vs. Red Sox. The game is one of 16 on the Friday MLB slate. See up-to-date lines for every game on our MLB odds page.)

Before making any MLB picks for that game or others in the evening, you NEED to see the latest predictions from the SportsLine Projection Model.

This model, which simulates every pitch of every game 10,000 times, had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line picks. It is off to a fast start in 2021, going 44-31 on top-rated MLB money-line picks through six weeks, returning over $700. Anyone following it has seen HUGE rewards.

Now, the model has set its sights on the MLB schedule for Friday. Using its top picks for the day, the model has generated a four-leg parlay that would pay 10-1! The best part is that the first game doesn't start until 7:10 p.m. ET, so you have plenty of time to enter your picks!

One of the MLB picks the model loves for Friday: The Dodgers (-213), behind ace Clayton Kershaw, win against the visiting Miami Marlins (+196), with first pitch set for 10:10 p.m. ET from Dodgers Stadium. The model also has three other picks, including a MUST-SEE underdog pick that pays serious plus-money! You ABSOLUTELY need to see it before locking in any MLB picks of your own.

So what significant underdog is strong value on Friday? And what other teams do you need include in your parlay for a HUGE payout of 10-1? ... Join SportsLine right now to find out which picks you should be all over on Friday, all from the model that was up more than $1,400 on MLB picks in 2019!