It's another packed Friday night MLB schedule on July 8, and the Yankees will try to continue their dominance of the AL East rival Red Sox as part of the 15-game slate. There also is a pitching rematch from Sunday Night Baseball when the Cardinals and Phillies open a four-game set in St. Louis. Philadelphia's Zack Wheeler won Sunday's duel with Adam Wainwright 4-0, and now the Cards will try to rebound from an extra-inning loss to the Braves on Thursday. Left-hander Nestor Cortes will go for his eighth win of the season for the Yankees, who took the series opener 6-5 on Thursday for their ninth win in their last 11 against Boston. Other notable matchups Friday night include the Giants visiting the Padres (9:40 p.m. ET) and the red-hot Mariners hosting the Blue Jays (10:10 p,m, ET).

First pitch in the Yankees vs. Red Sox series is at 7:10 p.m. ET. New York is the -160 favorite in the latest Red Sox vs. Yankees odds from Caesars Sportsbook, while Boston is a +135 underdog. Philadelphia is a -130 favorite in the Cardinals vs. Phillies game at 8:15 p.m. ET. (See up-to-date lines for every game on our MLB odds page.)

The 15-game MLB schedule brings tons of options for wagers and predictions, and you can cash in big if you combine your top picks into a parlay. Before you make any MLB picks or parlays, be sure to see the predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times and is 271-232 on top-rated MLB money-line picks since the start of the 2021 season, returning well over $500 for $100 players. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win the World Series. Anybody who has followed the model has seen profitable returns.

Now, the model has set its sights on the MLB schedule for Friday, July 8. Using its top picks for the day, the model has generated a four-leg parlay that would pay well over 16-1! The parlay doesn't start until 8:10 p.m. ET, giving you plenty of time to make your MLB picks.

We can tell you that one of the picks is the Brewers (-225) to beat the Pirates. But the model has three other selections, all of them underdogs that can help you cash in huge! You ABSOLUTELY need to see them before locking in any MLB picks of your own.

So which underdogs are MUST-BACKS on Friday night? And which teams do you need to include in your parlay for a payout of well over 16-1? ... Join SportsLine right now to find out which picks you should be all over on Friday, all from the model that is 271-232 on top-rated MLB money-line picks since the start of the 2021 season!