Angels two-way star Shohei Ohtani makes his last start before the All-Star break when he takes the mound for the Los Angeles Angels against the Houston Astros at Angel Stadium in Anaheim, Calif. For the second straight season Ohtani (8-4, 2.44 ERA) has made the American League All-Star team as both a pitcher and hitter. On Wednesday he will square off against the Astros' Cristian Javier. 

Los Angeles is a -120 favorite in the latest Angels vs. Astros odds from Caesars Sportsbook while Houston is a +100 underdog. First pitch is set for 9:38 p.m. ET. The game is one of 16 on the MLB schedule for Wednesday. (See up-to-date lines for every game on our MLB odds page.)

Before making any MLB picks or parlays, be sure to see the predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it is 275-236 on top-rated MLB money-line picks since the start of the 2021 season, returning more than $400 for $100 players. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win the World Series. Anybody who has followed the model has seen profitable returns.

Now, the model has set its sights on the MLB schedule for Wednesday, July 13. Using its top picks for the day, the model has generated a four-leg parlay that would pay well over 28-1! The parlay doesn't start until 6:40 p.m. ET, giving you plenty of time to make your MLB picks.

We can tell you that one of the picks is the A's (+158) to beat the Rangers. But the model has three other picks, including a play on a National League underdog! You ABSOLUTELY need to see them before locking in any MLB picks of your own.

So which underdog is a MUST-BACK? And what other teams do you need to include in your parlay for a payout of well over 28-1? ... Join SportsLine right now to find out which picks you should be all over on Wednesday, all from the model that is 275-236 on top-rated MLB money-line picks since the start of the 2021 season!