Memphis vs. Tulane odds, line: 2025 college football picks for Week 11 predictions from proven model

A pair of teams battling for American Conference supremacy will meet on Friday as the Tulane Green Wave visit the Memphis Tigers. Tulane (6-2, 3-1 American) saw its three-game win streak end last Thursday with a 48-26 defeat to UTSA. Memphis (8-1, 4-1 American) has won back-to-back outings after suffering its only loss of the year, and the Tigers defeated Rice, 38-14, on October 31. These are two of six teams in the American with a lone conference loss entering Week 11.

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Kickoff is at 9 p.m. ET from Simmons Bank Liberty Stadium in Memphis, Tenn. The Tigers are 3.5-point favorites in the latest Memphis vs. Tulane odds, while the over/under for total points scored is 53.5 via SportsLine consensus. 

Before making any Tulane vs. Memphis picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of over $2,000 for $100 players on its top-rated college spread football picks. Anyone following could have seen impressive returns.

The model has simulated Memphis vs. Tulane 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits over 60% of the time!

So who wins Tulane vs. Memphis, and which side of the spread hits over 60% of the time? Join SportsLine right now to see which side of the Memphis vs. Tulane spread you need to jump on, all from the computer model that has crushed its college football picks!

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