The Clemson Tigers return to the court for the first time in 12 days when they take on the Wake Forest Demon Deacons on Wednesday afternoon at Lawrence Joel Coliseum in Winston-Salem, N.C. Tip-off is set for 4:30 p.m. ET. The Tigers are favored by 3.5 points in the latest odds from William Hill Sportsbook, while the Over/Under for total points scored is 131.5 (See up-to-date odds for every game this week on our college basketball odds page.) 

Before making any Clemson vs. Wake Forest picks, be sure to check out what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of more than $2,500 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has set its sights on Wake Forest vs. Clemson. We can tell you that the model is leaning Over the total, and it also has generated a point-spread pick that is hitting in well over 50 percent of simulations. You ABSOLUTELY need to see it before locking in your own picks.

Who wins Clemson vs. Wake Forest? And which side of the spread hits in well over 50 percent of simulations? ... Join SportsLine right now to find out which side of the Wake Forest vs. Clemson spread you should be all over Wednesday, all from the model on a roll on college basketball picks!