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    Chargers vs. Colts line, picks: Advanced computer NFL model releases selections for Monday night showdown

    SportsLine's projection model generated selections for Monday's matchup between the Los Angeles Chargers and the Indianapolis Colts
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    The Los Angeles Chargers and Indianapolis Colts meet on Monday Night Football at 8:15 p.m. ET. Los Angeles is favored by 3.5 points at Caesars Sportsbook, while the over/under is set at 44.5 (see up-to-date odds for every game this week on our NFL odds page). 

    Before making any Chargers vs. Colts picks, you NEED to check out the NFL predictions from the SportsLine Projection Model..

    The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 16 of the 2022 NFL season on an incredible 157-113 run on top-rated NFL picks that dates back to the 2017 season. 

    The model ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

    The model knows the Chargers have at least 365 total yards in four of the last games, and Los Angeles is prolific through the air. The Chargers are No. 2 in the NFL with more than 270 passing yards per game, and Los Angeles has only 15 giveaways all season. The model also knows the Colts have strong defensive characteristics. Indianapolis allows opponents to convert only 36.8% of third down chances, and the Colts are in the top 12 of the NFL in total defense and passing defense. Indianapolis also stout against the run, with opponents averaging only 4.1 yards per carry.

    Now, it has set its sights on Chargers vs. Colts. We can tell you the model is leaning Over the total, and it also says one side of the spread hits more than 50% of the time! You ABSOLUTELY need to see it before locking in any NFL picks.

    Who wins Chargers vs. Colts? And which side of the spread hits more than 50% of the time? ... Join SportsLine right now to find out which side of the Chargers vs. Colts spread you should be all over Monday, all from the model on a roll on NFL picks!

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    JOIN NOW
    SportsLine Staff

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