The No. 3 Notre Dame Fighting Irish battle the Pittsburgh Panthers in a key Atlantic Coast Conference matchup on Saturday. Kickoff from Heinz Field in Pittsburgh is set for 3:30 p.m. ET. The Fighting Irish are 10-point favorites in the latest Notre Dame vs. Pittsburgh odds from William Hill, while the over-under for total points scored is 43.5 Before making any Notre Dame vs. Pittsburgh picks, be sure to check out the FBS college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past four-plus years, the proprietary computer model has generated a stunning profit of over $4,100 for $100 players on its top-rated college football picks against the spread. It is a sizzling 25-13 on top-rated picks through seven weeks of the 2020 college football season, returning over $700 in profit already. Anyone who has followed it has seen huge returns.

Now, it has set its sights on Notre Dame vs. Pittsburgh. We can tell you it's leaning Over, and it also says one side of the spread cashes in nearly 60 percent of simulations. You ABSOLUTELY need to see it before locking in any FBS college football picks of your own.

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