The BYU Cougars will take on the Arizona State Sun Devils on Saturday, September 18 at 10:15 p.m. ET at LaVell Edwards Stadium. The Cougars are 2-0 overall and 1-0 at home, while ASU is 2-0 overall and has yet to play on the road in 2021. BYU, led by New York Jets starting quarterback Zach Wilson, ended last season with an 11-1 overall record, while ASU finished its abbreviated 2020 season with a 2-2 mark.

The Sun Devils are favored by 3.5 points in the latest BYU vs. Arizona State odds from Caesars Sportsbook, and the over-under is set at 51. Before you make any Arizona State vs. BYU picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of over $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 3 of the 2021 season on a 67-50 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, it has simulated BYU vs. Arizona State 10,000 times and the results are in. We can tell you that the model is leaning Under on the point total, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins BYU vs. Arizona State? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!