The Arizona Wildcats take on the San Diego State Aztecs at 10 p.m. ET on Saturday at Arizona Stadium. 

San Diego State handled business in its first game, but Arizona is looking to rebound from a tough Week 1 loss. The Wildcats are favored by 1 point in the latest Arizona vs. San Diego State odds from Caesars Sportsbook, and the over-under is set at 46.5. Before you make any San Diego State vs. Arizona picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of over $3,600 for $100 players on its top-rated college football picks against the spread. It also enters Week 2 of the 2021 season on a 63-45 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, it has simulated Arizona vs. San Diego State 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in over 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Arizona vs. San Diego State? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks ... If you're already a member, see the picks below!