The Pac-12 Conference opens its season as the Arizona State Sun Devils take on the No. 20 USC Trojans on Saturday. Kickoff is set for noon ET from the Los Angeles Coliseum. The Trojans are 11-point favorites in the latest Arizona State vs. USC odds from William Hill, while the over-under for total points scored is 55.5 (find the current college football lines for every game this week in our college football odds section).

Before making any Arizona State vs. USC picks, be sure to check out the FBS college football predictions from the SportsLine Projection Model.

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Now, it has set its sights on Arizona State vs. USC. We can tell you it's leaning Under, and it's also generated an against-the-spread pick that cashes in almost 60 percent of simulations! You ABSOLUTELY need to see it before locking in any college football picks of your own.

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