It's an NFC West showdown when the San Francisco 49ers visit the Arizona Cardinals on Thursday Night Football. Kickoff is set for 8:20 p.m. ET. San Francisco is a 10-point favorite in the latest 49ers vs. Cardinals odds, while the over-under for total points scored is 43. Before you consider making any 49ers vs. Cardinals  picks, you NEED to check out the NFL predictions from the SportsLine Projection Model. 

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on its top-rated NFL picks since its inception four years ago. It has nailed its recent top-rated NFL picks, entering Week 9 of the 2019 NFL schedule on a strong 25-17 run that dates back to last season. 

It's also on an incredible 87-60 roll on top-rated NFL picks that dates back to the 2017 season, The model also ranked in the Top 10 on NFLPickWatch for the third year in a row on straight-up NFL picks and beat more than 96 percent of CBS Sports office pool players. Anyone who has followed it is WAY UP.  

Now, it has analyzed 49ers vs. Cardinals. We can tell you it's leaning over, and it says one side of the spread cashes in more than 50 percent of simulations! You ABSOLUTELY need to see it before locking in any NFL picks of your own.

So who wins 49ers vs. Cardinals? And which side of the spread cashes in over 50 percent of simulations? ... Join SportsLine right now to find out which side of the 49ers vs. Cardinals spread you should be all over on Thursday night, all from the advanced model that has returned almost $7,000 on top-rated NFL picks!