The No. 22 USC Trojans will take on the No. 16 Iowa Hawkeyes in the 2019 Holiday Bowl at 8 p.m. ET on Friday in San Diego. The Hawkeyes are two-point favorites in the latest USC vs. Iowa odds, while the Over-Under for total points scored is 53.5. Before making any USC vs. Iowa picks, be sure to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past four-plus years, the proprietary computer model has generated a stunning profit of almost $4,000 for $100 players on its top-rated college football picks against the spread. It also went a sizzling 8-2 on all picks against the spread during Championship Week. Anyone who has followed it has seen HUGE returns.

Now, it has set its sights on USC vs. Iowa. We can tell you it's leaning Under, and it's also generated an against the spread pick that cashes in nearly 70 percent of simulations! You ABSOLUTELY need to see it before locking in any college football picks of your own.

Who wins USC vs. Iowa in the Holiday Bowl? And which side of the spread can you bank on in nearly 70 percent of simulations? ... Join SportsLine right now to see which side of the USC vs. Iowa spread to back on Friday, all from the advanced model that has generated a stunning profit of almost $4,000 for $100 players on top-rated picks!