The San Francisco 49ers and Seattle Seahawks meet on Sunday Night Football to close out the regular season. Kickoff is set for 8:20 p.m. ET from CenturyLink Field in Seattle. San Francisco is a 3.5-point favorite in the latest 49ers vs. Seahawks odds, while the Over-Under for total points scored is 46. Before you consider making any 49ers vs. Seahawks picks, you NEED to check out the NFL predictions from the SportsLine Projection Model. 

The model, which simulates every NFL game 10,000 times, is up over $7,000 for $100 players on its top-rated NFL picks since its inception four-plus years ago. It has nailed its recent top-rated NFL picks, entering Week 17 of the 2019 NFL schedule on a strong 33-22 run that dates back to last season. It's also on an incredible 95-65 roll on top-rated NFL picks that dates back to the 2017 season.

The model ranked in the Top 10 on NFLPickWatch the past three years on straight-up NFL picks and beat more than 96 percent of CBS Sports office pool players last season. Anyone who has followed it is way up.

Now, it has analyzed 49ers vs. Seahawks. We can tell you it's leaning Over, and it also has generated a pick where one side of the spread cashes in more than 50 percent of simulations! You ABSOLUTELY need to see it before locking in any NFL picks of your own.

So who wins 49ers vs. Seahawks on Sunday Night Football? And which side of the spread hits over 50 percent of the time? ... Join SportsLine right now to find out which side of the 49ers vs. Seahawks spread you should be all over on Sunday, all from the advanced model that has returned over $7,000 on top-rated NFL picks!