In-state rivals clash when the Colorado State Rams and Colorado Buffaloes kick off their college football season on Friday at 10 p.m. ET from Broncos Stadium at Mile High in Denver. The Buffaloes have won the last four meetings and lead the all-time series 66-22-2. Colorado is a 12.5-point favorite in the latest Colorado State vs. Colorado odds, while the Over-Under for total points scored is 55.5. Before making any Colorado State vs. Colorado picks of your own, be sure to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times, and those who have followed it have seen massive returns. Over the past four years, this proprietary computer model has generated a jaw-dropping $4,530 profit for $100 bettors on its top-rated spread picks.

The model enters the first full weekend of the 2019 college football season on a blistering 49-29 run on all top-rated picks. It also called Miami (+7) covering against No. 8 Florida in the season opener and hit the under. Anybody who has been following it is WAY up.

Now, it has set its sights on Colorado State vs. Colorado. We can tell you the model is leaning Over, and it also says one side of the spread hits in well over 60 percent of simulations! You ABSOLUTELY need to see it before locking in any college football picks of your own.

So who wins Colorado State vs. Colorado? And which side of the spread can you bank on in well over 60 percent of simulations? ... Join SportsLine right now to find out which side of the Colorado State vs. Colorado spread you should be all over on Friday, all from the advanced model that is up more than $4,500 on its top-rated college football picks!