The top-ranked Clemson Tigers begin their ACC schedule on Saturday when they visit the Syracuse Orange. Kickoff from the Carrier Dome is set for 7:30 p.m. ET. The Tigers are 28-point favorites and the over-under for total points scored is 64.5 in the latest Clemson vs. Syracuse odds. Before making your Clemson vs. Syracuse picks, check out what the SportsLine Projection Model has to say. 

The SportsLine Projection Model simulates every FBS college football game 10,000 times, and those who have followed it have seen massive returns. Over the past four years, this proprietary computer model has generated a jaw-dropping $4,530 profit for $100 bettors on its top-rated spread picks.

The model enters Week 3 of the 2019 college football season on a blistering 18-6 run on its top-rated picks. It also called Colorado's (+158) straight-up upset of Nebraska and was all over Army (+23) against No. 10 Michigan in a game the Black Knights pushed to overtime and covered with a ton of room to spare. Anybody who has been following it is WAY UP. 

Now, it has set its sights on Clemson vs. Syracuse. We can tell you it's leaning Under, and it also says one side of the spread cashes in nearly 60 percent of simulations! You ABSOLUTELY need to see it before locking in any college football picks of your own.

So who wins Syracuse vs. Clemson? And which side of the spread can you bank on in nearly 60 percent of simulations? ... Join SportsLine right now to find out which side of the Clemson vs. Syracuse spread you should be all over on Saturday, all from the advanced model that is up more than $4,500 on its top-rated college football picks!