It's an early ACC matchup when the Miami Hurricanes host the No. 5 Louisville Cardinals on Tuesday night. Tipoff is set for 6:30 p.m. ET. The Cardinals are 6.5-point favorites in the latest Louisville vs. Miami odds, while the Over-Under for total points scored is 145.5. Before making any of your Louisville vs. Miami picks, be sure to check out the college basketball predictions from the SportsLine Projection Model.  

This model, which simulates every game 10,000 times, crushed its top-rated against-the-spread picks last season, going 211-176 while returning $1,740 to $100 players. Anybody who has followed it has seen huge returns.   

Now, it has broken down Louisville vs. Miami. We can tell you it's leaning Under, and it's also generated a STRONG against the spread pick that cashes in well over 60 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks of your own.

Who wins Louisville vs. Miami? And which side of the spread is hitting well over 60 percent of the time? ... Join SportsLine right now to see which side of the Louisville vs. Miami spread to back on Tuesday, all from the advanced model on a 211-176 run on top-rated picks!