The Virginia Tech Hokies and the Virginia Cavaliers are set to square off in an ACC matchup at 7 p.m. ET Wednesday at Cassell Coliseum. The Hokies are 15-12 overall and 11-5 at home, while Virginia is 19-7 overall and 5-4 on the road. Virginia is fourth in the ACC; Virginia Tech is 11th. The Cavaliers are favored by 2.5 points in the latest Virginia Tech vs. Virginia odds, while the Over-Under is set at 113.5. Before you make any Virginia vs. Virginia Tech picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

This model, which simulates every game 10,000 times, has crushed its top-rated college basketball picks against the spread the past three years, returning $2,770 to $100 players. It also entered Week 17 of the 2019-20 season on a 66-40 run on all top-rated college basketball picks. Anybody who followed it has seen huge returns.

Now, it has simulated Virginia Tech vs. Virginia 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in almost 70 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Virginia Tech vs. Virginia? And which side of the spread is hitting in almost 70 percent of simulations? ...Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks... If you're already a member, see the picks below!