The Brigham Young Cougars will take on the Southern California Trojans at 2:30 p.m. ET Tuesday at Mohegan Sun Arena. The Cougars are favored by three-points in the latest BYU vs. USC odds from William Hill Sportsbook, and the Over-Under is set at 145. Before you make any USC vs. BYU picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every FBS college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of almost $2,600 for $100 players on its top-rated college basketball picks against the spread. It's also off to a fast start in the 2020-21 season, going 4-1 on its top-rated picks and returning over $300. Anyone who has followed it has seen huge returns.

Now, it has simulated BYU vs. USC 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 70 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins BYU vs. USC? And which side of the spread is hitting in well over 70 percent of simulations? ... Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.