The Indianapolis Colts will take on the Carolina Panthers at 1 p.m. ET on Sunday at Lucas Oil Stadium. Indianapolis is 6-8 overall and 4-3 at home, while Carolina is 5-9 overall and 3-4 on the road. Indianapolis is favored by 6.5 points in the latest Colts vs. Panthers odds, while the Over-Under is set at 46.5. Before you make any Panthers vs. Colts picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The model, which simulates every NFL game 10,000 times, is up over $7,000 for $100 players on its top-rated NFL picks since its inception four years ago. It has nailed its recent top-rated NFL picks, entering Week 16 of the 2019 NFL schedule on a strong 33-22 run that dates back to last season. It's also on an incredible 95-65 roll on top-rated NFL picks that dates back to the 2017 season. The model ranked in the Top 10 on NFLPickWatch the past three years on straight-up NFL picks and beat more than 96 percent of CBS Sports office pool players last season. Anyone who has followed it is way up.

Now, it has simulated Colts vs. Panthers 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick where one side of the spread has all the value. You absolutely need to see it before locking in your own picks.

So who wins Colts vs. Panthers? And which side of the spread has all the value? ...Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks.