Louisiana will take on Ohio at 2 p.m. ET on Saturday at Peden Stadium. The Bobcats are favored by three points in the latest Ohio vs. Louisiana odds, while the Over-Under is set at 67.5. Before you make any Ohio vs. Louisiana picks and college football predictions on either side, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every FBS college football game 10,000 times, and those who have followed it have seen massive returns. Over the past four years, this proprietary computer model has generated a jaw-dropping $4,530 profit for $100 bettors on its top-rated college football against the spread picks. The model enters Week 4 on a blistering 30-10 run on its top-rated picks. It also called Kentucky (+9.5) covering against No. 9 Florida and No. 5 Oklahoma (-23.5) covering against UCLA in Week 3. Anybody who has been following it is way up.

Now, it has simulated Ohio vs. Louisiana 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Ohio vs. Louisiana? And which side of the spread is hitting in well over 60 percent of simulations? ...Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!