The No. 15 Villanova Wildcats and the No. 18 Marquette Golden Eagles are set to square off in a Big East matchup at 8:30 p.m. ET Wednesday at Finneran Pavilion. The Wildcats are favored by 5 points in the latest Villanova vs. Marquette odds, while the Over-Under is set at 144. Before you make any Marquette vs. Villanova picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

This model, which simulates every game 10,000 times, has crushed its top-rated college basketball picks against the spread the past three years, returning $2,770 to $100 players. It also enters Week 15 of the 2019-20 season on a 42-27 run on all top-rated college basketball picks. Anybody who followed it has seen huge returns.

Now, it has simulated Villanova vs. Marquette 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread has all the value. You absolutely need to see it before locking in your own picks.

So who wins Villanova vs. Marquette? And which side of the spread has all the value? ...Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks... If you're already a member, see the picks below!