The Southern Miss Golden Eagles and the Louisiana Tech Bulldogs will face off in a Conference USA clash Saturday at 7:30 p.m. ET at Carlisle-Faulkner Field at M.M. Roberts Stadium. Louisiana Tech ended last year second in the West Division, while the Golden Eagles ended up third. 

The Golden Eagles are favored by 5.5 points in the latest Southern Miss vs. Louisiana Tech odds from William Hill, up from 4 at the open. The Over-Under is set at 58.5, up from 54.5 at the open. Before you make any Louisiana Tech vs. Southern Miss picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past four years, the proprietary computer model has generated a stunning profit of over $3,700 for $100 players on its top-rated college football picks against the spread. It is a stunning 9-0 on top-rated picks through two weeks of the 2020 college football season, returning almost $800 in profit already. Anyone who has followed it has seen huge returns.

Now, it has simulated Southern Miss vs. Louisiana Tech 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in almost 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Southern Miss vs. Louisiana Tech? And which side of the spread is hitting in almost 60 percent of simulations? ...Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!