The Arizona Cardinals will take on the Detroit Lions at 4:25 p.m. ET on Sunday at State Farm Stadium. The Lions are favored by 2.5 points over the Cardinals in the latest Detroit vs. Arizona odds, while the Over-Under is set at 46.5. Before you make any Lions vs. Cardinals picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

This model, which simulates every NFL game 10,000 times, is up over $7,000 for $100 players on its top-rated NFL picks since its inception four years ago. It absolutely nailed its top-rated NFL picks in 2018-19, finishing the season on a sizzling 16-6 run. For the year, it went 30-15 on all top-rated picks (20-8 against the spread), extending its two-year run to a strong 78-49. The model ranked inside the Top 10 on NFLPickWatch.com for the third straight year on straight-up NFL picks and beat over 96 percent of CBS Sports office pool players. Anyone who has followed it is way up.

Now, it has simulated Cardinals vs. Lions 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in almost 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Cardinals vs. Lions? And which side of the spread is hitting in almost 60 percent of simulations? ... Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks... If you're already a member, see the picks below!