The  No. 14 Villanova Wildcats will take on the DePaul Blue Demons at 8:30 p.m. ET on Tuesday at Finneran Pavilion. Villanova is 12-3 overall and 7-0 at home, while DePaul is 12-4 overall and 4-1 on the road. The Wildcats are third in the Big East; DePaul is 10th. The Wildcats are favored by 9.5 points in the latest Villanova vs. DePaul odds, while the Over-Under is set at 142.5. Before you make any DePaul vs. Villanova picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The model, which simulates every game 10,000 times, has crushed its top-rated college basketball picks against the spread the past three years, returning $2,770 to $100 players. Anybody who followed it during that span has seen huge returns.

Now, it has simulated Villanova vs. DePaul 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Villanova vs. DePaul? And which side of the spread is hitting in over 50 percent of simulations? ...Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks... If you're already a member, see the picks below!