The Detroit Pistons will take on the Portland Trail Blazers at 7 p.m. ET Wednesday at Little Caesars Arena. The Pistons are 13-33 overall and 8-13 at home, while Portland is 28-18 overall and 14-9 on the road.  Portland is favored by 7.5 points in the latest Pistons vs. Blazers odds from William Hill Sportsbook, and the Over-Under is set at 221. Before you make any Blazers vs. Pistons picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every NBA game 10,000 times, and it has returned more than $8,800 in profit on its top-rated NBA picks over the past two-plus seasons. The model is up more than $800 on its top-rated picks this season, and dating back to last year, it entered Week 15 of the 2020-21 NBA schedule on a stunning 93-59 roll on top-rated NBA picks against the spread. Anybody who has followed it has seen huge returns.

Now, it has simulated Pistons vs. Blazers 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in almost 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Pistons vs. Blazers? And which side of the spread is hitting in almost 60 percent of simulations? ...Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NBA picks... If you're already a member, see the picks below!