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    49ers vs. Raiders prediction, odds, line, spread: Proven model reveals NFL picks, best bets for Week 17, 2022

    The SportsLine projection model simulated Las Vegas vs. San Francisco and released its picks, predictions, and best bets for this NFL Week 17 game
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    Former Bay Area rivals are set to square off when Jarrett Stidham and the Las Vegas Raiders host Brock Purdy and the San Francisco 49ers in a NFL Week 17 matchup at 4:05 p.m. ET on Sunday at Allegiant Stadium in Las Vegas. The Raiders are 6-9 overall and 4-2 at home, while San Francisco is 11-4 overall and 4-3 on the road. The 49ers are 10-5 against the spread and the Raiders are 7-8 ATS in 2022.

    San Francisco is favored by 9.5 points in the latest 49ers vs. Raiders odds from Caesars Sportsbook, and the over/under is set at 41 points. Before you make any Raiders vs. 49ers picks or predictions, you'll want to see what the SportsLine Projection Model is saying.

    The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 17 of the 2022 NFL season on an incredible 158-113 run on top-rated NFL picks that dates back to the 2017 season. The model ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

    Now, it has simulated 49ers vs. Raiders 10,000 times and the results are in. We can tell you that the model is leaning Under on the point total, and it also says one side of the spread hits well over 50% of the time. You absolutely need to see it before locking in your own picks.

    So who wins 49ers vs. Raiders? And which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks.

    GET VEGAS EXPERT PICKS FOR NFL, MLB, NBA, CBB, GOLF, NHL, HORSE RACING AND MORE - PLUS ADVANCED COMPUTER SIMULATIONS, WINNING TOOLS, AND MORE!

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    SportsLine Staff

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