The top-seeded Gonzaga Bulldogs meet the sixth-seeded USC Trojans in a 2021 NCAA Tournament Elite Eight matchup on Tuesday. Tip-off from Lucas Oil Stadium in Indianapolis is set for 7:15 p.m. ET. William Hill Sportsbook lists the Bulldogs as 8.5-point favorites, while the Over-Under for total points scored is 153 in the latest USC vs. Gonzaga odds (see up-to-date lines for every game on our college basketball odds page). 

Before making any USC vs. Gonzaga picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of $2,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

Now, it has set its sights on USC vs. Gonzaga. We can tell you the model is leaning Over the total, and it also says one side of the spread hits almost 60 percent of the time! You ABSOLUTELY need to see it before locking in any college basketball picks.

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