ANALYSIS: Louisville is playing just its second game in about three weeks due to a COVID break and will be missing its second-best all-around player in David Johnson (12.7 ppg, 5.9 rpg, 3.4 apg) plus reserves Josh Nickelberry and Aidan Igiehon. The Cards were utterly embarrassed in their return from the break Saturday at North Carolina. The Irish, meanwhile, are 4-1 ATS in their last five games as road underdogs.