Light heavyweight champion Alex Pereira will defend his title against former champion Jamahal Hill to headline the historic UFC 300 card Saturday. The five-round main event tops the main UFC 300 fight card starting at 10 p.m. ET from T-Mobile Arena in Las Vegas. Pereira is a -125 favorite (risk $125 to win $100), while Hill is offered at +105 (risk $100 to win $105) in the UFC 300 odds. Before settling your picks for UFC 300, make sure you see the MMA predictions and betting advice from SportsLine expert Daniel Vithlani.

Vithlani is a highly analytical UFC bettor who has been a consistent winner for SportsLine members since making his debut in January 2023 with a 5-0 record for UFC 283. In the last eight UFC pay-per-view events, Vithlani has gone 6-2 on main-event picks and his main-card selections in that span have netted his followers a profit of more than $1,500. 

His highlights include calling an upset for Sean O'Malley (+210) against Aljamain Sterling (-250) at UFC 292 as part of a 4-1 main card and his UFC 299 winners included underdog selections on Dustin Poirier (+190) against Benoit Saint Denis (-230) and Michael Page (+110) against Kevin Holland (-130). Anyone who has followed him is WAY UP!

This week at UFC 300, we can tell you Vithlani is backing Max Holloway (+170) to get his hand raised against Justin Gaethje (-250) in a lightweight showdown on the main card. "Holloway's cardio and chin are unmatched. He takes damage better than anyone and stays sharp even when the fight isn't going his way," Vithlani told SportsLine.

Vithlani has strong picks for Pereira vs. Hill and other bouts on the UFC 300 card. He's also backing a fighter who "will have boxing and power advantages" to emerge with a dominant victory! You ABSOLUTELY need to see his UFC 300 picks before making any of your own!

Who wins Pereira vs. Hill, and which UFC 300 fighters are MUST-BACKS? Join SportsLine now to see which fighters you need to be all over Saturday, all from the expert  who has profited more than $1,500 on the last eight UFC pay-per-view cards!