Bantamweight champion Sean O'Malley will make the first defense of his belt on Saturday in the main event of UFC 299 in a rematch against No. 5-ranked contender Marlon Vera. The main UFC 299 fight card is set for 10 p.m. ET from the Kaseya Center in Miami.

O'Malley is a -280 favorite (risk $280 to win $100), while Vera is a +230 underdog (risk $100 to win $230) in the latest UFC 299: O'Malley vs. Vera 2 odds. Before settling your picks for UFC 299: O'Malley vs. Vera 2, make sure you see the MMA predictions and betting advice from SportsLine expert Daniel Vithlani.  

Before making any UFC 299: O'Malley vs. Vera 2 picks of your own, you NEED to see the latest MMA predictions from SportsLine MMA analyst Kyle Marley. Over the past three-plus years, $100 bettors who have followed Marley's picks are up nearly $11,000! 

The accomplished MMA analyst has provided consistent winners for SportsLine members for the past five years. His accomplishments include hitting five consecutive main-event underdog winners in 2020 following the UFC's brief pause in action because of the pandemic. Anyone who has followed Marley is WAY UP!

This week at UFC 299: O'Malley vs. Vera 2, we can tell you Marley is backing Kevin Holland (-135) against Michael Page (+115) in one of the bouts on the main card. "Holland is a lethal striker and he should be throwing more volume," Marley told SportsLine. "He should have a big edge on the ground if he looks for takedowns. Holland has more ways to win this fight, so if he doesn't get knocked out by something crazy, I like him to get his hand raised."

Marley also has strong picks for O'Malley vs. Vera 2 and other bouts on the UFC 299 card. He's also backing a combatant who "is one of the scariest fighters in the UFC" to emerge with a huge victory! You MUST see his UFC 299 picks before making any of your own.

Who wins UFC 299: O'Malley vs. Vera 2? And which other fighters to do you need to back? Join SportsLine now to see which fighters you need to be all over Saturday, all from the expert who's up nearly $11,000 on MMA picks!